|
Symbol Name ID |
Irak4
interleukin-1 receptor-associated kinase 4 MGI:2182474 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased B cell proliferation |
abnormal NK cell physiology |
abnormal macrophage physiology |
decreased circulating interferon-gamma level |
decreased circulating interleukin-1 level |
decreased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
abnormal cytokine level |
abnormal cytokine secretion |
abnormal chemokine secretion |
decreased interferon-alpha secretion |
decreased interferon-beta secretion |
decreased interleukin-12b secretion |
decreased interleukin-6 secretion |
decreased tumor necrosis factor secretion |
decreased acute inflammation |
decreased susceptibility to endotoxin shock |
increased susceptibility to bacterial infection |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Irak4m1Btlr/Irak4m1Btlr | ||||||||||||||||||||
| Irak4tm1Aki/Irak4tm1Aki | * | |||||||||||||||||||
| Irak4tm1Gram/Irak4tm1Gram | ||||||||||||||||||||
| Irak4tm1Lix/Irak4tm1Lix | ||||||||||||||||||||
| Irak4tm1Yeh/Irak4tm1Yeh | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools